Novel Movable Typing for Personalized Vein?Chips in Large Scale: Recapitulate Patient?Specific Virchow's Triad and its Contribution to Cerebral Venous Sinus Thrombosis
نویسندگان
چکیده
The Vein-Chip recapitulates CVST Virchow's triad and enables systematic characterization of venous thrombogenesis with respect to fibrin formation platelet aggregation. Distinct from the arterial setting, platelets universally adhere across entire CVS independent stenotic geometry flow disturbance. Intriguingly, propagates along direction, but exclusively deposits inner vessel wall. Upon inflammatory endothelial injury, deposition mirrors outer wall, still not in lumen. Together, promises future applications for personalized thrombotic assessment monitoring.
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ژورنال
عنوان ژورنال: Advanced Functional Materials
سال: 2023
ISSN: ['1616-301X', '1616-3028']
DOI: https://doi.org/10.1002/adfm.202214179